(Lipoprotein Lipase): The LPL test examines variations in the LPL gene that codes for the lipoprotein lipase enzyme. Variants in this gene can impact lipid metabolism and increase the risk of cardiovascular diseases, including atherosclerosis and coronary artery disease
Tests Included
LPL
FOXO1
(Forkhead Box O1): The FOXO1 test analyzes the FOXO1 gene, which plays a role in regulating cell growth, differentiation, and apoptosis. Alterations in this gene have been associated with various conditions, including cancer, diabetes, and neurodegenerative diseases.
FAAH
(Fatty Acid Amide Hydrolase): The FAAH test investigates variations in the FAAH gene, which encodes an enzyme involved in the breakdown of endocannabinoids. Changes in this gene may affect endocannabinoid signaling and have been associated with conditions such as pain sensitivity, anxiety, and substance abuse disorders.
F5
(Coagulation Factor V): The F5 test examines mutations in the F5 gene, which is responsible for producing coagulation factor V. Certain genetic variants in this gene, such as the Factor V Leiden mutation, can increase the risk of abnormal blood clotting disorders, including deep vein thrombosis (DVT) and pulmonary embolism.
F2
(Coagulation Factor II): The F2 test analyzes variations in the F2 gene, which codes for prothrombin, a clotting protein. Specific mutations in the F2 gene, such as the prothrombin G20210A mutation, can increase the risk of abnormal blood clotting disorders similar to those associated with F5 mutations.
CAT
(Catalase): The CAT test assesses variations in the CAT gene, which provides instructions for producing the enzyme catalase. Catalase plays a crucial role in neutralizing harmful reactive oxygen species in cells. Genetic variants in the CAT gene may impact the antioxidant defense system and potentially contribute to conditions associated with oxidative stress, such as cardiovascular diseases, neurodegenerative disorders, and cancer.
DRD3
(Dopamine Receptor D3): Genetic variants in this gene have been associated with conditions such as schizophrenia, bipolar disorder, addiction, and movement disorders.
DRD2
(Dopamine Receptor D2): Certain genetic variants in this gene have been linked to an increased risk of developing conditions such as schizophrenia, substance abuse disorders, and restless legs syndrome.
DRD1
(Dopamine Receptor D1): Alterations in this gene have been implicated in conditions such as schizophrenia, attention-deficit/hyperactivity disorder (ADHD), and addiction.
CYP3A4
(Cytochrome P450 3A4): The CYP3A4 test examines variations in the CYP3A4 gene, which plays a significant role in drug metabolism. Genetic variants in this gene can impact the activity of the CYP3A4 enzyme, influencing the way certain medications are processed and potentially affecting their effectiveness or toxicity.
CYP2C9
(Cytochrome P450 2C9): The CYP2C9 gene is responsible for metabolizing a wide range of medications. Genetic variants in this gene can affect the metabolism of drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) and anticoagulants, leading to variations in drug response and potential side effects.
CYP1A1
(Cytochrome P450 1A1): The CYP1A1 test investigates variations in the CYP1A1 gene, which is involved in the metabolism of various environmental toxins and carcinogens. Genetic variants in this gene can impact the detoxification process and potentially increase the susceptibility to certain cancers and other health conditions.
COL3A1
(Collagen Type III Alpha 1 Chain): Mutations in this gene can lead to connective tissue disorders such as Ehlers-Danlos syndrome, which affects the strength and elasticity of the skin, joints, and blood vessels.
CLOCK
(Circadian Locomotor Output Cycles Kaput): The CLOCK gene is involved in regulating circadian rhythms and the body's internal clock. Genetic variants in this gene can impact sleep patterns and potentially contribute to conditions like insomnia, mood disorders, and metabolic disturbances.
APOC3
(Apolipoprotein C3): The APOC3 test investigates variations in the APOC3 gene, which is involved in regulating lipid metabolism and triglyceride levels. Genetic variants in this gene can influence the risk of developing cardiovascular diseases, such as coronary artery disease and hypertriglyceridemia.
APOA2
(Apolipoprotein A2): The APOA2 test examines variations in the APOA2 gene, which codes for apolipoprotein A2. Genetic variants in this gene have been associated with differences in lipid profiles, including cholesterol levels, and may contribute to the risk of cardiovascular diseases.
ANK3
(Ankyrin 3): The ANK3 test analyzes variations in the ANK3 gene, which is involved in the functioning of neuronal cells. Genetic variants in this gene have been associated with conditions such as bipolar disorder and schizophrenia.
ALDH2
(Aldehyde Dehydrogenase 2): The ALDH2 test investigates variations in the ALDH2 gene, which codes for aldehyde dehydrogenase 2 enzyme. Genetic variants in this gene can impact alcohol metabolism and have been linked to alcohol sensitivity and an increased risk of certain cancers.
AKT1
(AKT Serine/Threonine Kinase 1): The AKT1 gene is involved in cell growth, survival, and metabolism. Genetic variants in this gene have been associated with various conditions, including psychiatric disorders, cancer, and cardiovascular diseases.
ADRB3
(Beta-3 Adrenergic Receptor): Genetic variants in this gene have been implicated in metabolic disorders, such as obesity, insulin resistance, and type 2 diabetes.
ACSL1
(Acyl-CoA Synthetase Long Chain Family Member 1): The ACSL1 gene is involved in fatty acid metabolism. Genetic variants in this gene can affect lipid metabolism and potentially contribute to conditions such as metabolic syndrome and cardiovascular diseases.
UCP3
(Uncoupling Protein 3): The UCP3 gene is involved in energy expenditure and metabolism. Genetic variants in this gene have been studied in relation to obesity, insulin resistance, and metabolic disorders.
HO-1
(Heme Oxygenase 1): Genetic variants in this gene can impact antioxidant and anti-inflammatory responses and have been linked to various conditions, including cardiovascular diseases and certain cancers.
UCP2
(Uncoupling Protein 2): The UCP2 gene is involved in energy metabolism and regulation of reactive oxygen species. Genetic variants in this gene have been associated with obesity, diabetes, and other metabolic disorders.
CYP2C19
(Cytochrome P450 2C19): CYP2C19 plays a role in metabolizing certain medications, including proton pump inhibitors and antiplatelet drugs. Genetic variants in this gene can affect the enzyme's activity, leading to differences in drug response and potentially influencing the effectiveness of these medications.
CYP1B1
(Cytochrome P450 1B1): The CYP1B1 is involved in metabolizing various substances, including environmental toxins and certain medications. Genetic variants in this gene have been associated with the risk of developing certain cancers, including breast, lung, and prostate cancer.
CETP
(Cholesteryl Ester Transfer Protein): Genetic variants in this gene have been associated with changes in high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels, potentially impacting the risk of cardiovascular diseases.
NOS3
(Nitric Oxide Synthase 3): This enzyme is involved in the production of nitric oxide, a molecule that regulates blood vessel function. Genetic variants in this gene can impact cardiovascular health and contribute to conditions such as hypertension and endothelial dysfunction.
CYP1A2
(Cytochrome P450 1A2): The CYP1A2 is responsible for metabolizing several medications and environmental toxins. Genetic variants in this gene can influence the rate of caffeine metabolism and may affect individual responses to caffeine consumption and susceptibility to certain diseases, including cancer and cardiovascular disorders.
HTR1A
(Serotonin Receptor 1A): Serotonin is a neurotransmitter involved in mood regulation and other physiological processes. Genetic variants in this gene have been associated with psychiatric disorders such as depression, anxiety, and schizophrenia.
PLIN1
(Perilipin 1): The PLIN1 is involved in lipid metabolism and storage within fat cells. Genetic variants in this gene can influence the risk of developing obesity, insulin resistance, and metabolic disorders.
NFE2L2
(Nuclear Factor, Erythroid 2 Like 2): Genetic variants in this gene can impact antioxidant responses and have been studied in relation to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
BDNF
(Brain-Derived Neurotrophic Factor): Genetic variants in this gene have been associated with psychiatric disorders, neurodegenerative diseases, and cognitive function.
SULT1A1
(Sulfotransferase 1A1): Genetic variants in this gene can impact drug metabolism and have been associated with susceptibility to certain cancers.
APOE
(Apolipoprotein E): Genetic variants in this gene, such as APOE ε4 allele, are associated with an increased risk of developing Alzheimer's disease and cardiovascular diseases.
IL6R
(Interleukin 6 Receptor): Genetic variants in this gene can impact inflammatory processes and have been associated with various conditions, including autoimmune diseases and cardiovascular disorders.
GSTT1
(Glutathione S-Transferase Theta 1): Genetic variants in this gene can influence detoxification capacity and may be associated with cancer susceptibility and response to environmental toxins.
IL1
(Interleukin 1): Genetic variants in these genes have been associated with various inflammatory conditions, autoimmune diseases, and susceptibility to certain cancers.
PPARGC1A
(PPAR Gamma Coactivator 1 Alpha): Genetic variants in this gene can influence metabolic processes, including glucose and lipid metabolism, and may be associated with conditions such as obesity, diabetes, and cardiovascular diseases.
TCN2
(Transcobalamin 2): Genetic variants in this gene can affect the availability of vitamin B12 in the body, potentially leading to vitamin B12 deficiency and related health conditions.
DAO
(Diamine Oxidase): Genetic variants in this gene can impact histamine metabolism, potentially contributing to conditions such as histamine intolerance, allergies, and migraines.
GSTM1
(Glutathione S-Transferase Mu 1): Genetic variants in this gene can influence detoxification capacity and may be associated with susceptibility to certain cancers and response to environmental toxins.
VDR
(Vitamin D Receptor): Genetic variants in this gene can impact the functioning of the vitamin D receptor and may be associated with conditions such as osteoporosis, autoimmune diseases, and certain cancers.
GC
(Group-Specific Component): Genetic variants in this gene can influence vitamin D levels and may have implications for bone health, immune function, and other vitamin D-related processes.
SLC23A1
(Solute Carrier Family 23 Member 1): Genetic variants in this gene can impact the absorption and utilization of vitamin C in the body, potentially influencing overall vitamin C status and related health outcomes.
FUT2
(Fucosyltransferase 2): This gene encodes an enzyme that plays a role in determining blood group antigens and affects the ability to secrete certain antigens in bodily fluids like saliva and intestinal mucus.
NBPF3
(Neuroblastoma breakpoint family, member 3): This gene is associated with neuroblastoma, a type of cancer that develops from nerve cells in infants and young children.
PEMT
(Phosphatidylethanolamine N-methyltransferase): This gene encodes an enzyme involved in the production of phosphatidylcholine, a component of cell membranes and lipoproteins.
FADS1
(Fatty acid desaturase 1): This gene encodes an enzyme that is involved in the conversion of essential fatty acids to their longer-chain, more unsaturated forms.
FADS2
(Fatty acid desaturase 2): This gene is another member of the fatty acid desaturase family and is also involved in the conversion of essential fatty acids.
HFE
(High Fe iron gene): Variants of this gene are associated with hereditary hemochromatosis, a condition where the body absorbs too much iron from the diet, leading to iron overload.
GPX1
(Glutathione peroxidase 1): This gene encodes an enzyme that plays a crucial role in protecting cells from oxidative damage by reducing hydrogen peroxide and organic hydroperoxides.
ADIPOQ
(Adiponectin): This gene codes for the adiponectin hormone, which is involved in regulating glucose levels and fatty acid breakdown and has a role in metabolic processes.
PON1
(Paraoxonase 1): This gene encodes an enzyme involved in the metabolism of certain drugs and detoxification of harmful compounds. It is also associated with antioxidant activity.
OPRM1
(Opioid receptor mu 1): This gene codes for the mu-opioid receptor, which is involved in mediating the effects of opioid drugs and plays a role in pain perception and response to opioid medications.
HNMT
(Histamine N-methyltransferase): This gene encodes an enzyme that is responsible for the breakdown of histamine in the body. Variations in this gene can affect histamine levels and may be related to conditions such as allergies and histamine intolerance.
CBS
Cystathionine beta-synthase): This gene codes for an enzyme involved in the metabolism of the amino acid homocysteine. Mutations in this gene can lead to homocystinuria, a disorder characterized by elevated homocysteine levels and can affect the cardiovascular and nervous systems.
CYP2R1
(Cytochrome P450 family 2 subfamily R member 1): This gene encodes an enzyme responsible for converting vitamin D to its active form. Variations in this gene can impact vitamin D metabolism and may influence an individual's vitamin D levels and related health outcomes.
APOA5
(Apolipoprotein A5): This gene codes for a protein involved in the metabolism of triglycerides, a type of fat found in the blood. Variations in this gene are associated with altered triglyceride levels and may influence the risk of cardiovascular diseases.
MTR
(5-Methyltetrahydrofolate-homocysteine methyltransferase): This gene codes for an enzyme involved in the folate metabolism pathway. Variations in this gene can impact the conversion of homocysteine to methionine, affecting homocysteine levels in the body.
MTRR
(5-Methyltetrahydrofolate-homocysteine methyltransferase reductase): This gene encodes an enzyme that plays a role in the recycling of vitamin B12 in the folate metabolism pathway. Variations in this gene can also impact homocysteine levels and vitamin B12 metabolism.
SHBG
(Sex Hormone-Binding Globulin): This test measures the levels of SHBG, a protein produced by the liver that binds to sex hormones (such as testosterone and estrogen) in the bloodstream. SHBG levels can influence the availability and activity of sex hormones in the body.
COMT
(Catechol-O-Methyltransferase): This gene codes for an enzyme that is involved in the breakdown and inactivation of neurotransmitters such as dopamine, norepinephrine, and epinephrine. Variations in this gene can impact the metabolism of these neurotransmitters and may be associated with certain mental health conditions.
DIO2
(Type 2 Deiodinase): This gene codes for an enzyme that converts inactive thyroid hormone (T4) to its active form (T3) in various tissues. Variations in this gene can affect thyroid hormone levels and may contribute to thyroid-related health issues.
GSTP1
(Glutathione S-transferase pi 1): This gene codes for an enzyme involved in detoxification processes, specifically the metabolism of certain toxins and carcinogens. Variations in this gene may influence an individual's ability to neutralize harmful substances.
BHMT
(Betaine-homocysteine methyltransferase): This gene codes for an enzyme involved in the metabolism of homocysteine. BHMT helps convert homocysteine to methionine when folate levels are low. Variations in this gene can impact homocysteine levels and may affect cardiovascular health.
MTHFD1
(Methylenetetrahydrofolate dehydrogenase 1): This gene is part of the folate metabolism pathway and plays a role in the production of purines, which are essential for DNA synthesis. Variations in this gene can influence folate metabolism and potentially impact cell division and DNA synthesis.
FTO
(Fat mass and obesity-associated gene): This gene is associated with obesity and body weight regulation. Variations in this gene have been linked to an increased risk of obesity and may influence an individual's response to diet and exercise.
MC4R
(Melanocortin 4 receptor): This gene codes for a receptor involved in appetite regulation and energy balance. Variations in this gene can impact hunger and satiety signals, potentially contributing to obesity.
MTHFR
(Methylenetetrahydrofolate reductase): This gene is another important component of the folate metabolism pathway and is involved in converting homocysteine to methionine. Variations in this gene can affect homocysteine levels and may influence cardiovascular and neurological health.
SOD2
(Superoxide Dismutase 2): This gene codes for an enzyme which plays a critical role in neutralizing harmful free radicals in cells, specifically the superoxide anion. Variations in this gene can affect the body's antioxidant defense system and may be associated with oxidative stress-related conditions.
ACE
(Angiotensin-Converting Enzyme): This gene codes for the ACE enzyme, which plays a role in regulating blood pressure by converting angiotensin I to angiotensin II. Variations in this gene may influence an individual's risk of hypertension and cardiovascular diseases.
DRD4
(Dopamine Receptor D4): This gene codes for a dopamine receptor that is involved in neurotransmission and has been associated with personality traits, behavior, and response to certain medications. Variations in this gene may be linked to attention-deficit/hyperactivity disorder (ADHD) and other neuropsychiatric conditions.
HIF1A
(Hypoxia-Inducible Factor 1-alpha): This gene codes for a transcription factor that plays a central role in the cellular response to low oxygen levels (hypoxia). Variations in this gene may influence an individual's response to hypoxic conditions and can be relevant in various disease contexts, including cancer
CRP
(C-Reactive Protein): This test measures the levels of C-reactive protein, an inflammatory marker produced by the liver. Elevated CRP levels are associated with inflammation in the body and may indicate an increased risk of cardiovascular diseases and other inflammatory conditions.
COL12A1
(Collagen Type XII Alpha 1 Chain): This gene codes for a component of type XII collagen, which is involved in connective tissue formation. Variations in this gene may be associated with certain connective tissue disorders or musculoskeletal conditions.
CKM
(Creatine Kinase M): This gene codes for the muscle-specific creatine kinase enzyme, which plays a role in energy metabolism in muscle cells. Variations in this gene may be relevant in conditions related to muscle energy production and certain muscle disorders.
AMPD1
(Adenosine Monophosphate Deaminase 1): This gene codes for an enzyme that is involved in energy metabolism. Variations in this gene may influence an individual's ability to tolerate intense exercise and can be relevant in exercise-related conditions.
ADRB2
(Beta-2 Adrenergic Receptor): This gene codes for a receptor involved in the body's response to the neurotransmitter adrenaline (epinephrine) and other adrenergic agents. Variations in this gene can impact an individual's response to medications targeting this receptor, such as those used for asthma or COPD
TIMP4
(Tissue Inhibitor of Metalloproteinases 4): This gene codes for a protein that regulates the activity of certain enzymes involved in tissue remodeling. Variations in this gene may be relevant in conditions related to tissue health and repair.
TAS2R38
(Taste Receptor Type 2 Member 38): This gene codes for a taste receptor involved in perceiving certain bitter tastes. Variations in this gene can influence an individual's ability to taste certain bitter compounds and may affect dietary preferences and food choices
SIRT1
(Sirtuin 1): This gene codes for an enzyme involved in cellular processes such as aging, DNA repair, and metabolism. Variations in this gene may be associated with aging-related conditions and metabolic disorders
PPARA
(Peroxisome Proliferator-Activated Receptor Alpha): This gene codes for a nuclear receptor that regulates the expression of genes involved in lipid metabolism. Variations in this gene can influence an individual's response to dietary fat and may be relevant in metabolic conditions
LEPR
(Leptin Receptor): This gene codes for a receptor involved in the regulation of appetite and energy balance. Variations in this gene may impact an individual's response to the hormone leptin, which plays a role in appetite control and metabolism.
CYP2D6
(Cytochrome P450 Family 2 Subfamily D Member 6): This gene codes for an enzyme involved in the metabolism of a wide range of medications, including antidepressants, antipsychotics, and pain medications. Variations in this gene can affect an individual's response to these medications.
CHRNA5
(Cholinergic Receptor Nicotinic Alpha 5 Subunit): This gene codes for a subunit of the nicotinic acetylcholine receptor. Variations in this gene have been associated with nicotine addiction and smoking behavior.
ACE2
(Angiotensin-Converting Enzyme 2): This gene codes for an enzyme that plays a critical role in the renin-angiotensin system, which regulates blood pressure and fluid balance. ACE2 has also received significant attention during the COVID-19 pandemic because it is the receptor used by the SARS-CoV-2 virus to enter cells
UCP1
(Uncoupling Protein 1): This gene codes for a protein that is involved in heat production in brown adipose tissue (brown fat). Variations in this gene may be relevant in thermogenesis and metabolic rate.
TCF7L2
(Transcription Factor 7-Like 2): This gene codes for a transcription factor involved in the regulation of gene expression. Variations in this gene have been associated with an increased risk of type 2 diabetes and can influence insulin signaling
PPARG
(Peroxisome Proliferator-Activated Receptor Gamma): This gene codes for a nuclear receptor that plays a role in regulating glucose and lipid metabolism. Variations in this gene may be associated with insulin resistance and obesity-related conditions.
OXTR
(Oxytocin Receptor): This gene codes for the oxytocin receptor, which binds to the hormone oxytocin. Variations in this gene may influence an individual's social behavior, bonding, and emotional responses.
MMP1
(Matrix Metalloproteinase 1): This gene codes for an enzyme that plays a role in tissue remodeling and repair. Variations in this gene may be relevant in conditions related to tissue health and wound healing.
IL6
(Interleukin 6): This gene codes for the interleukin-6 cytokine, which is involved in inflammation and the immune response. Variations in this gene may be associated with altered immune system function and susceptibility to inflammatory conditions.
IRS1
(Insulin Receptor Substrate 1): This gene codes for a protein that is involved in insulin signaling and glucose metabolism. Variations in this gene can impact insulin sensitivity and may be relevant in type 2 diabetes and metabolic disorders
GDF5
(Growth Differentiation Factor 5): This gene codes for a protein that plays a role in skeletal development and joint health. Variations in this gene have been associated with certain musculoskeletal conditions, such as osteoarthritis
FABP2
(Fatty Acid-Binding Protein 2): This gene codes for a protein involved in the transport of fatty acids. Variations in this gene may impact an individual's response to dietary fat and may be relevant in metabolic conditions.
EPHX1
(Epoxide Hydrolase 1): This gene codes for an enzyme involved in the metabolism of certain environmental toxins and xenobiotics. Variations in this gene can affect an individual's detoxification capacity
CYP19A1
(Cytochrome P450 Family 19 Subfamily A Member 1): This gene codes for an enzyme involved in the synthesis of estrogen. Variations in this gene may influence an individual's hormone levels and may be relevant in hormone-related conditions.
CYP17A1
(Cytochrome P450 Family 17 Subfamily A Member 1): This gene codes for an enzyme involved in the synthesis of sex hormones, including androgens and estrogens. Variations in this gene can impact an individual's hormone levels and may be relevant in conditions related to hormone production and metabolism.
COL1A1
(Collagen Type I Alpha 1 Chain): This gene codes for a component of type I collagen, which is the most abundant collagen type in the body and is a major structural protein in connective tissues such as bone, skin, and tendons. Variations in this gene may be associated with certain connective tissue disorders or bone-related conditions.
CACNA1C
(Calcium Voltage-Gated Channel Subunit Alpha1 C): Variations in this gene have been associated with certain cardiovascular conditions, including heart rhythm disorders and cardiac arrhythmias
AGT
(Angiotensinogen): This gene codes for angiotensinogen, a precursor protein involved in the renin-angiotensin system that regulates blood pressure and fluid balance. Variations in this gene may influence an individual's risk of hypertension and cardiovascular diseases.
ACVR1B
(Activin A Receptor Type 1B): This gene codes for a receptor involved in cell signaling pathways, particularly in the regulation of growth and development. Variations in this gene may be relevant in conditions related to bone formation and metabolism.
ACTN3
(Alpha-Actinin-3): This gene codes for a structural protein primarily found in fast-twitch muscle fibers. Variations in this gene can influence an individual's muscle performance and athletic abilities.
VEGFA
(Vascular Endothelial Growth Factor A): This gene codes for a protein that plays a crucial role in promoting the growth of blood vessels. Variations in this gene may be associated with altered angiogenesis and vascular-related conditions.
UGT2B17
(UDP Glucuronosyltransferase Family 2 Member B17): This gene codes for an enzyme involved in the metabolism of certain drugs and xenobiotics. Variations in this gene can affect an individual's drug metabolism and response to medications.
UGT2B15
(UDP Glucuronosyltransferase Family 2 Member B15): Variations in this gene may impact an individual's drug metabolism and response to medications
SRD5A1
(5-alpha Reductase Type 1): Variations in this gene can influence an individual's androgen levels and may be relevant in conditions related to hormone regulation and metabolism.
SLCO1B1
(Solute Carrier Organic Anion Transporter Family Member 1B1): Variations in this gene can impact an individual's response to certain medications and their drug metabolism.
SLC2A2
(Solute Carrier Family 2 Member 2): This gene codes for the glucose transporter 2 (GLUT2), which is involved in glucose uptake in certain tissues, including the liver and pancreas. Variations in this gene may be relevant in conditions related to glucose metabolism and diabetes.
PPARD
(Peroxisome Proliferator-Activated Receptor Delta): This gene codes for a nuclear receptor that plays a role in lipid metabolism and inflammation. Variations in this gene may be associated with metabolic conditions and cardiovascular diseases.
OGG1
(8-Oxoguanine DNA Glycosylase 1): This gene codes for an enzyme involved in DNA repair, specifically the removal of DNA damage caused by oxidative stress. Variations in this gene may influence an individual's response to oxidative stress and their risk of certain diseases related to DNA damage.
TNF
(Tumor Necrosis Factor): This gene codes for the tumor necrosis factor-alpha (TNF-alpha), a pro-inflammatory cytokine involved in the immune response and inflammation. Variations in this gene have been associated with altered immune system function and susceptibility to inflammatory conditions.
NQO1
(NAD(P)H Dehydrogenase Quinone 1): This gene codes for an enzyme involved in the detoxification of quinones and other toxic compounds. Variations in this gene can impact an individual's ability to metabolize certain drugs and xenobiotics.
NAT2
(N-Acetyltransferase 2): This gene codes for an enzyme involved in the metabolism of various drugs and environmental chemicals. Variations in this gene can influence an individual's drug metabolism and response to medications.
NAT1
(N-Acetyltransferase 1): This gene codes for an enzyme involved in the metabolism of certain drugs and environmental chemicals. Variations in this gene can influence an individual's drug metabolism and response to medications.
MMP3
(Matrix Metalloproteinase 3): This gene codes for an enzyme that plays a role in tissue remodeling and repair. Variations in this gene may be relevant in conditions related to tissue health and wound healing.
MMP2
(Matrix Metalloproteinase 2): This gene codes for an enzyme involved in the breakdown of collagen and other components of the extracellular matrix. Variations in this gene may be associated with certain musculoskeletal conditions and tissue disorders.
ITGB3
(Integrin Beta-3): This gene codes for a subunit of a cell surface receptor called integrin, which is involved in cell adhesion and signaling. Variations in this gene have been associated with certain cardiovascular conditions, including susceptibility to arterial thrombosis.
HLA
(Human Leukocyte Antigen): This gene family codes for proteins involved in the immune system's recognition of foreign substances and regulation of immune responses. Variations in HLA genes are associated with an individual's susceptibility to certain autoimmune diseases and their response to infections.
GSTO2
(Glutathione S-Transferase Omega 2): This gene codes for an enzyme involved in the detoxification of certain compounds and the protection against oxidative stress. Variations in this gene may impact an individual's ability to neutralize harmful substances.
FOXO3
(Forkhead Box O3): This gene codes for a transcription factor that plays a role in regulating genes involved in cellular responses to stress and longevity. Variations in this gene have been linked to longevity and age-related diseases.
How It Works
1
Order Your Test
24-28 hours after the order is placed, you'll get an email from our partner, Rupa Health, who will help facilitate the shipment from the lab. Test kits will be shipped and received in 2-4 business days.
2
Take Your Test
You will receive personalized testing instructions from Rupa Health This will include instructions for your tests, and assistance finding a nearby phlebotomist if your test requires a blood draw.
3
Analyze Your Test
Results are comprehensive and will give you in-depth data into your health. View sample results when browsing tests. You may download these results and share them with your medical provider.
Frequently Asked Questions
When do I receive my results?
Your results will be e-mailed to you in 10-30 days after receiving the sample. Turn around time varies depending on the lab test ordered.
What should I do if I take the test and I receive an abnormal result?
No consultations are provided at this time. Please make an appointment with your primary care physician and discuss your results with him/her. We do not offer medical advice, treatment, or prescriptions.
Do you take insurance?
No, we do not accept insurance. You may however use your HSA/ FSA.
I’ve received my results, now what?
At this time we don’t offer physician follow up appointments. The results can be downloaded and taken with you to discuss with your primary care physician.
Are these tests available in every state?
Due to state restrictions, Proactive Wellness lab tests are not available to residents of New York, New Jersey and Rhode Island.
Do I need to be referred by a doctor to order a test?
No. No referral required.
How do I share my results with my doctor?
You may download the results and either print or email them to share with your doctor.
Can I stop going to my primary care physician?
No, this is not in replacement of your annual physical. Your annual physical blood work will measure standard lab work that we do not test for.
How often should I get tested?
Testing is generally recommended every 6 months- 1 year.
How accurate are my results?
Each laboratory we use to help you get tested is CLIA-certified, which means they must meet or exceed high precision, accuracy and validity standards.